Abstract

Role of prebiotic and probiotic in the management of chronic kidney disease patients

Author(s):Mathew George, Lincy Joseph and Deepa George

Chronic Kidney disease is more common in Indian population today. Hence the need of medications for chronic kidney disease also increased now a days. This study is designed to investigate the role of Prebiotics and probiotics in the management of chronic kidney disease patient. Oral administration of a probiotic formulation of selected microbial strains may extend renoprotection via intraintestinal extraction of toxic waste solutes in patients with chronic kidney disease (CKD) . The idea behind the research is to prevent the development of key damaging uremic toxins by targeting the process of bacterial protein fermentation in the gut. People with kidney disease have been shown to have a disturbed gut flora, which promotes the increased production of those harmful toxins. By supplementing patients with a specific combination of bacteria (probiotics) and beneficial fibre to support the growth of the good bacteria (prebiotics), it improve the health of the gut, suppressing the growth of bad bacteria and therefore decreasing the production of the toxins. In turn this should assist in delaying further kidney disease progression and improve heart health

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