Abstract

Is Hyperuricemia in Falciparum Malaria Infected Children Explains the Etiology of Burkitt’s Lymphoma?

Falciparum malaria still represents the big obstacle to communities in Sub-Sahara African countries, and more concentrated efforts against the COVID-19 pandemic may influence the lives of millions of children in that malariaendemic area. Hyperuricemia associated with plasmodium falciparum infection reflects the density of parasitemia and it may lead to kidney injury, resulting in low vitamin D production. Furthermore, hyperuricemia leads to high levels of pro-inflammatory cytokines counting interferon γ-induced protein, which is invested vitamin D deficiency in the development of Burkitt’s lymphoma. Experimental research is required.

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