International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Abstract
Exploring Potential Intervention of Convalescent Plasma-Derived Hyper-immunized Antibodies to Combat COVID-19: A Mini-Review
Author(s):Viveeyan Saikia and Archana Deka*Globally, COVID-19 caused by SARS-CoV-2 has resulted in millions of infections and several thousand deaths. Amid the race for the development of vaccines and antiviral drugs, convalescent plasma therapy has emerged as an emergency treatment for SARS-CoV-2 infected patients. In this review, we provide an overview of the use of passive immunization-based therapy as an immediate measure during novel viral infections when no other treatments are available. We also discuss the benefits and challenges faced by the use of convalescent plasma therapy in the COVID-19 pandemic. Further, we attempted to stress the relevance of convalescent plasma-derived hyper-immunized immunoglobulins with high neutralizing activity as a potential therapeutic intervention for COVID-19.
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