Abstract

Comparsion of Intralesional Triamcinolone Acetonide and Combination of 5-Flurouracil and Triamcinolone in Treatment of Keliods

Background: Keloids are a common problem with significant recurrence. Despite many options available, there is no standard acceptable treatment for keloid. This study has compared the intralesional triamcinolone acetonide and a combination of 5-fluorouracil in the treatment of keloids. Methods: This is a randomized study. 60 patients were randomly allocated into two groups. Group 1-TAC+5FU, Group 2-TAC alone. The intralesional injection was given every 3 weeks till 24 weeks. Results: There was a reduction in scar height, vascularity, pigmentation, and pliability. Improvement in terms of height, vascularity, and pliability was faster with TAC+5FU. Conclusion: TAC+5FU combination was effective in keloids in comparison to Triamcinolone Acetonide (TAC) alone. The combination offered the balanced benefits of faster and more effective responses.

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