Abstract

Comparison of Serum Calcium, Serum Magnesium and Serum Electrolytes in Patients of Preeclampsia and Normal Pregnant Women-A Cross Sectional Study

Background: Preeclampsia is clinically defined by hypertension and proteinuria, with or without pathological edema. Preeclampsia is a multisystem disorder that complicates about 4%-18% of pregnancies in developing nations and constitutes a major source of morbidity and mortality worldwide. Preeclampsia may be life-threatening for both mother and child, increasing both fetal and maternal morbidity and mortality. About 10%-15% of maternal deaths are directly associated with preeclampsia. Objective: To compare the changes in the level of serum calcium, serum magnesium, and serum electrolytes in patients with preeclampsia and normal pregnant women. Material and Method: Serum calcium, serum magnesium, and serum electrolytes were estimated in 50 cases of preeclampsia and 50 controls of normal pregnant women. 5 ml of blood was collected with clot activator vaccutte and assayed on Micro lab Rx- 50V Biochemistry Analyzer. Result: The levels of serum calcium, serum magnesium, and serum electrolytes are found to be decreased in pre-eclamptic patients (p<0.001) as compared to normal pregnant women. Serum calcium levels were found to decrease in pre-eclamptic patients (7.624 ± 0.84) as compared to normal pregnant women (8.52 ± 0.80). Serum magnesium levels were found to decrease in pre-eclamptic patients (1.47 ± 0.25) as compared to normal pregnant women (1.79 ± 0.18). Serum sodium levels were found to decrease in pre-eclamptic patients (131.46 ± 6.96) as compared to normal pregnant women (139.92 ± 7.86). Serum potassium levels were found to decrease in preeclamptic patients (3.39 ± 0.52) as compared to normal pregnant women (3.67 ± 0.38). Conclusion: We concluded that the levels of serum calcium, serum magnesium, and serum electrolytes were decreased significantly in patients with preeclampsia (p<0.001). Results also prove that these biomarkers can be used as important parameters for the diagnosis of preeclampsiaa.

• Full-Text
• PDF