GET THE APP

Comparison between Effect of Intravenous Lignocaine and Ketamine in Alleviating Propofol Injection Pain in Patients Undergoing Surgeries under General Anaesthesia | Abstract
Logo

International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)

Abstract

Comparison between Effect of Intravenous Lignocaine and Ketamine in Alleviating Propofol Injection Pain in Patients Undergoing Surgeries under General Anaesthesia

Author(s):Saravanakumar Rajan*, Sivagurunathan Jawahar and Ashok Kulasekhar

Background: Propofol is the most commonly used intravenous inducing agent. Sharp, burning, or aching pain on injection is a major problem. The cardiovascular response to the pain can aggravate adverse events in patients with a history of coronary artery disease Small boluses of ketamine, magnesium, dexmedetomidine, ondansetron, dexamethasone, lignocaine hydrochloride, ketorolac, metoclopramide, and opioids have been tried. Objectives: To compare analgesic effects of using intravenous ketamine and lignocaine in alleviating pain following propofol injection. Methods: A prospective randomized double-blinded study was conducted in Chettinad Hospital and Research Institute, Kelambakkam among 50 participants undergoing surgeries under general anaesthesia . Tourniquet was applied midarm, Group L was given 21.3 mg of 2% lignocaine and Group K was given 15mg of ketamine. Tourniquet was removed after 30 seconds and then 1/3rd dose of a total dose of 2 mg/kg propofol was given. The degree of injection pain was evaluated using the Mccririck Hunter scale. Results: The pain score on propofol injection was similar in both groups. Among the patients, 54% reported no pain, in that 76% of patients were in Group L and 52% of patients in Group K. Mccririck and hunter pain scale ratings between the two groups are similar with a p-value of more than 0.05. Conclusions: The pre-treatment of 15 mg ketamine is as effective as 21.3 mg 2% lignocaine in reducing the severity of propofol injection pain.


Select your language of interest to view the total content in your interested language

Archive
Scope Categories
  • Clinical Research
  • Epidemiology
  • Oncology
  • Biomedicine
  • Dentistry
  • Medical Education
  • Physiotherapy
  • Pulmonology
  • Nephrology
  • Gynaecology
  • Dermatology
  • Dermatoepidemiology
  • Otorhinolaryngology
  • Ophthalmology
  • Sexology
  • Osteology
  • Kinesiology
  • Neuroscience
  • Haematology
  • Psychology
  • Paediatrics
  • Angiology/Vascular Medicine
  • Critical care Medicine
  • Cardiology
  • Endocrinology
  • Gastroenterology
  • Infectious Diseases and Vaccinology
  • Hepatology
  • Geriatric Medicine
  • Bariatrics
  • Pharmacy and Nursing
  • Pharmacognosy and Phytochemistry
  • Radiobiology
  • Pharmacology
  • Toxicology
  • Clinical immunology
  • Clinical and Hospital Pharmacy
  • Cell Biology
  • Genomics and Proteomics
  • Pharmacogenomics
  • Bioinformatics and Biotechnology