Kikuchi disease is a rare benign self limited lymphadenopathy. It is often associated with Systemic Lupus Erythematosus which can be diagnosed before; at the same time or after a diagnosis of Kikuchi disease is made. Again SLE is usually associated with APLA syndrome. Furthermore both SLE and Kikuchi disease can be complicated by HPS. We present a unique case in which Kikuchi disease and SLE were diagnosed together and disease course was complicated by Hemophagocytic syndrome (HPS). SLE was also associated with Anti Phospholipid Antibody Syndrome (APS) in this patient.
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