Abstract

An Effect of Serum Uric Acid Levels in Hypertension

Background: Hypertension (HTN or HT), also known as High Blood Pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. Worldwide, raised blood pressure is estimated to cause 7.5 million deaths, about 12.8% of the total of all deaths. Elevated levels of serum uric acid are strongly associated with the development and progression of hypertension and renal diseases, but whether uric acid plays a causal role or whether it simply acts as an indicator in patients at risk for these conditions remains controversial. Many authorities do not consider an increased uric acid to be a true risk factor for cardiovascular diseases, because patients with hyperuricemia mostly have other well-established risk factors for cardiovascular conditions like hypertension, renal disease, obesity, dyslipidaemias, and insulin resistance. This study was aimed to evaluate the levels of uric acid in hypertensive cases and normotensive controls. Material and Method: This study was conducted on 60 individuals in whom 30 were considered as cases and they had hypertension apart from any other non-communicable diseases. 30 healthy individuals were also taken as controls. This study was conducted in a tertiary care center. Results: As we compared both groups, we found a significant correlation between uric acid and hypertension. Statistical analysis was done on SPSS by using Karl’s Pearson’s correlation. Conclusion: Analyzed levels are shown that as systolic and diastolic blood pressure so that suggestion for future references is to maintain the blood pressure according to the guidelines as well as maintain the food restrictions and give preferences to physical exercise.

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