International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Xinran Zhang
Department of Life Science, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2AZ, UKPublications
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Review
Roles of iPSC in Advancing Treatments for Neurological Disorders
Author(s): Xinran Zhang*
Historically, disease research in neuroscience faced limitations due to species barriers and constraints with human samples. The advent of iPSC-induced neurons represents a significant breakthrough for academic and pharmaceutical research. Interdisciplinary collaborations have played a pivotal role in advancing iPSC technology. These collaborations have yielded innovative technologies, enhanced our understanding of cellular interactions and expanded iPSC applications. Despite progress, challenges persist, including concerns about tumorigenicity, immune rejection, inherent heterogeneity, and difficulty in recapitulating sporadic diseases. Scalability issues and the absence of age-associated cellular features in iPSC models are notable drawbacks. This concise review examines recent advancements in iPSC technology, focusing on its application in addressing neurological diseases. It delve.. Read More»
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