International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Venkataraman Sritharan
Global Medical Education and Research Foundation, Lakdikapul, Telangana, IndiaPublications
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Research
Targeting Multidrug Resistant A. Baumannii to Evaluate Anti-Biofilm and Anti-Quorum Sensing Potential of Some Compounds
Author(s): Saipriya Kamaraju, Venkataraman Sritharan* and Archana Giri
Background: The continuing search for new and novel antimicrobials for their potential as anti-biofilm and anti-quorum sensing agents has turned to many plant products possessing broad-spectrum anti-microbial activities. This potential has gained importance recently because the plant secondary metabolites exhibit anti-quorum sensing activity without interfering with the growth of the organism which thus would minimize the development of multidrug resistance. A. baumannii was the test organism in this study and we used carbapenem-resistant and sensitive clinical isolates. We have evaluated the anti-biofilm and anti-quorum sensing potential of two popular plant sources, namely mango seed kernels and guava leaves. Commonly used antimicrobial food preservative ε-Poly lysine was also evaluated for its anti-quorum sensing potential. Methods: Ethanol.. Read More»
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