Research
Rolapitant: Effects of an Antiemetic Agent on the Growth of Developing Chick Embryo
Author(s): Vishram Singh, Yogesh Yadav and Sohel Solanki*
Aim: The purpose of this study was to determine the effect of Rolapitant, an antiemetic agent, on chick embryo
development in 200 white leghorn chicken eggs used that met the inclusion-exclusion criteria.
Material and method: The present study utilized 200 eggs, randomly assigned to experimental groups A and B and control groups a and b.
Eggs incubated in the presence of Rolapitant had their Rolapitant dose increased on the fifth day of incubation from
0.18 mg to 0.36 mg. In contrast to the control groups, all of the subjects in the treatment groups received the same
amount of normal saline. Eggs were broken on the twentieth day of incubation, and embryos were extracted on the
same day.
Results: The weight and CRL of the chick embryos were measured, and gross anatomical malformations
wer.. Read More»
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