International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Shrabanthi Jana
Department of Anesthesia and Critical Care, SSIMS & RC, Davangere, Karnataka, IndiaPublications
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Research
Methemoglobinaemia Following Insecticide Poisoning-A Case Series
Author(s): Mamatha HK*, Anasuya Hegde, Lakshmi KV and Shrabanthi Jana
Methemoglobinaemia is an impaired state of oxygen delivery to tissues, seen when Ferrous iron of haem is oxidized to Ferric iron. Ingestion of nitrobenzene (rarely indoxacarb) containing pesticides either accidentally or with a suicidal intent leads to Methemoglobinaemia. Nitrobenzene is a pale yellow oily liquid with a characteristic bitter almond smell. It is used as an intermediate in the synthesis of aniline dyes, manufacture of benzidine, quinoline, azobenzene, rubber chemicals, screening paints, etc. Methemoglobinaemia results due to the intermediates (nitrobenzene and phenylhydroxylamine) formed during the metabolism of nitrobenzene by the reduction of aniline. Indoxacarb is an oxadiazine pesticide used for the control of cotton ball worm and native budworm in cotton and soya beans. Indoxacarb metabolizes to produce aniline metabolites and aromatic compounds that produce methem.. Read More»
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