International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Salim Hussein Hassan
IraqPublications
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Research
SARS-CoV-2 Genes Mutations Are a Challenge behind Its High Contagiosity: A Review
Author(s): Mohammed Abdulridha Merzah, Shewaye Fituma Natae and Salim Hussein Hassan*
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) has threatened global health security and raised a major international health concern. The new genetic background of this virus has existed due to mutations in either structural proteins, nonstructural proteins, or both. Spike glycoprotein recombination was presumed as a cause of cross-species transmission. To undertake a narrative review of the predisposing genetic variations and mutations of SARS-CoV-2, this is presumed to endorse its high contagiosity. Keyword search on a database of Medline-PubMed, Embase, and Science Direct was conducted. Relevant journals and bibliographies list of primary articles were screened manually. Relevant articles on novel Coronavirus 2 (nCoV-2) mutations were identified. This review revealed six main aspects of nCoV-2: high affinity to Angiotensin-Converting Enzyme 2 (ACE2) due to the variation.. Read More»
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