International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Iffat Zareen Ahmed
Department of Bioengineering, Integral University, Dasauli, Kursi Road, Lucknow, Uttar Pradesh, IndiaPublications
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Research
Exploring the Therapeutic and Biomedical Potential of Silver Nanoparticles Biosynthesized by Phycocyanin Extracts from a Marine Cyanobacteria
Author(s): Rupali Kaur, Shailendra Kumar Singh, Abhishek Bharadwaj, Iffat Zareen Ahmed and Shanthy Sundaram*
The study aimed to synthesize phycocyanin-mediated silver nanoparticles (Ag-CNPs) using pigment extracts from Synechococcus BDUSM13 as a green nano-synthesis procedure, an alternative for the toxic chemical route. Biosynthesized Ag-CNPs were characterized and analyzed for their therapeutic (e.g. antibacterial) and biomedical (e.g. anticancer) potential. Ag-CNPs were spherical in shape, crystalline, and small width-to-length ratio with a 4 nm to 20.9 nm diameter range. They also unveiled a wide range of inhibition spectrum activity against clinical bacterial strains such as Campylobacter sp., Shigella sp., Salmonella typhi, Bacillus subtilis, and Klebsiella sp. Ag-CNPs showed the highest inhibition against Klebsiella (13.5 mm) and B. subtilis (13.3 mm) strains whereas the lowest zone of inhibition was observed against Shigella (8.0 mm) at 100 μg/mL Ag-CNPs. The cytotoxic analysis on.. Read More»
DOI: O
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