Elias Adugna

Department of Pharmacology and Toxicology, School of Pharmacy, College of Medicine and Health Sciences, Mizan-Tepi University, Aman Campus, Southwest, Ethiopia

Publications

• Research   
  In-vitro Antibacterial Activity of the 80% Methanolic Leaf Extract of Maytenus gracilipes (Welw. ex Oliv) Exell. (celastraciae) against Some Pathogenic Bacteria
  Author(s): EslemanYessuf, Elias Adugna, Dejen Nureye*, Muktar Sano Kedir, Workineh Woldeselassie Hammeso, Nebeyi Fisseha and TeshaleWorku
  
  Background: Challenges by drug-resistant bacteria have stimulated renewed interest in medicinal plants as a major source of new medicines. The leaf of Maytenus gracilipes has been used as ethnomedicine for the treatment of tonsillitis and ear infections in Ethiopia. However, its antimicrobial potential has not been evaluated. This study aimed to screen the antibacterial activities of M. gracilipes leaves. Methods: In this study, the antibacterial activities of crude methanolic leaf extract were tested against two Gram-positive and three Gram-negative bacteria using the agar well diffusion method at different concentrations (50 mg/ml, 100 mg/ml, and 200 mg/ml). Augmentin 0.3 mg/disc and Ciprofloxacin 0.05 mg/disc were used as a standard drug. The minimum inhibitory concentration of the crude extract was determined by the broth dilution method. A preliminary phytoconstituent analysis wa.. Read More»
  

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