International Journal of Medical Research & Health Sciences (IJMRHS)
ISSN: 2319-5886 Indexed in: ESCI (Thomson Reuters)
Alok Bhardwaj
Departments of Biotechnology, Mugla University, Mathura, UP, IndiaPublications
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Research
Resistance, Phylogenetic Analysis of Pathogenic Escherichia coli in Human Isolate and their Sensitivity with Plant Extracts
Author(s): Geetika Gupta*, Ashok Kumar and Alok Bhardwaj
19 human stool samples were investigated for E. coli pathoyping, phylogenetic analysis, antibiotic resistance pattern, and photosensitivity. 78.94% of samples have the presence of the uspA gene of E. coli. Pathotypes revealed 33.33% Enteropathogenic E. coli (EPEC), 6.66% Enterotoxigenic E. coli (ETEC), but none of the isolates was found positive for EIEC. Phylogenetic markers grouped as (A, B, and D), which were belonged to the D2 group in 40% isolates, 40% isolates belonged to the B group and 20% belongs to the A1 group. Resistances to standard antibiotics/antibacterial were observed with cefixime and cefotaxime 93.33%, 86.66% ceftriaxone and 60% cefepime, 93.33% methicillin, furazolidone (26.66%) and nitrofurantoin 73.33%, sulphadiazine 93.33%,co-trimoxazole 86.66% and trimethoprim 60%, doripenem 46.66%, meropenem and ertapenem 20%, amoxicillin/clavulanic acid, tetracycline and (gat.. Read More»
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