A special issue on Nursing: Current Scenario and Future Development - Articles are invited.

THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES

Authors: B.Lakshmi, M.Swarajya Lakshmi, Rohini

Int J Med Res Health Sci.2015;4(4):837-840 | pdf PDF Full Text

ABSTRACT

 Introduction: Drug resistance is a serious medical problem. Indiscriminate use of antibiotics has led to a state where multi drug resistant bacteria have become increasingly prevalent. Therefore regular surveillance of important pathogens and their resistant pattern is mandatory. Aim: To find out prevalence of organisms causing infection and their sensitivity pattern. Material and methods: 676 clinical samples were screened among which 156 Gram Negative(GN) Isolates were processed for their antibiotic sensitivity profile against 12 different antibiotics. Results: Escherichia coli is the most common isolate of 156 gram negative isolates. Among all antibiotics, ampicillin is least sensitive (22%). Antibiotics with good sensitivity are Imipenam, Meropenam (100%), Levofloxacin 94%, Amikacin 89% Ciprofloxacin 79%, Gentamycin 77%. Pseudomonas is 100% sensitive to Amikacin. Conclusion: Antibiotic resistance in our area is still moderate. It is essential to test for older generation antibiotics before deciding on higher antibiotics for treatment which will have a tremendous impact on the treatment as well as cost effectiveness.  Regular surveillance helps in implementing better therapeutic strategies.

Keywords: Antibiogram, Gram negative isolates, Imipenam, Multi drug resistance, older generation antibiotics.

How to Cite this Article

.

Pubmed Style:


B.Lakshmi, M.Swarajya Lakshmi, Rohini. THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES .Int J Med Res Health Sci. 2015;4(4):837-840.


Web Style:


B.Lakshmi, M.Swarajya Lakshmi, Rohini. THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES.


AMA (American Medical Association) Style:


B.Lakshmi, M.Swarajya Lakshmi, Rohini. THERAPEUTIC IMPORTANCE OF OLDER GENERATION ANTIBIOTICS ON GRAM NEGATIVE ISOLATES .Int J Med Res Health Sci. 2015;4(4):837-840.

International Journal of Medical Research & Health Sciences © 2012-16 [Last updated: July 2016] by AspiringDigital