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The Effect of Palm Pollen Extract on Polycystic Ovary Syndrome (POS) in Rats

Authors: Hojatollah Karimi Jashni, Hossein Kargar Jahromi and Zahra Bagheri

Int J Med Res Health Sci.317-321 | pdf PDF Full Text

The positive effects of Palm pollen extract on the potential of fertility and folliculogenesis process in female genus
have been reported in several studies. So, this is study is aimed to evaluate the effects of Palm pollen extract on
induced- polycystic ovary syndrome (PCOS) in rats. A number of 48 adult female Wistar rats were divided in this
experimental study into 6 groups of 8 each. Control group: the rats in this group were kept in a normal condition
until the end of the experiment. They did not receive any substances. Sham group: sesame oil (the solvent of
estradiol valerate) was injected to the rats in this group at the first day of the experiment.After 60 days, they were
given distilled water (the solvent of Palm pollen) per the body weight for 21consecutive days. 4 mg estradiol
valerate in 2 ml sesame oil was injected intramuscularly to the rats in the other groups. Moreover they experienced
the special conditions of each group, including: PCOS 1 control group: the rats in this group were killed after 60
days. PCOS 2 control group: the rats in this group were killed after 81 days. The experimental 1 group: after 60
days, the rats in this group were orally administered 200 mg/kg of Palm pollen extract for 21 days. The
experimental 2 group: after 60 days, the rats in this group were orally administered 400 mg/kg of Palm pollen
extract for 21 days. At the end of the experiment period, blood samples were obtained to evaluate serum levels of
FSH, LH, estrogen and progesterone. The ovaries were also removed and studied with light microscopy after
weighing and cutting of the tissues. LH and estrogen levels in the PCOS group + 400 mg/kg of Palm pollen extract
showed a significant decrease compared to the PCOS group (p<0.05). FSH and progesterone levels in the PCOS
group + 400 mg/kg of Palm pollen extract showed a significant increase compared to the PCOS 1 and PCOS 2
groups (p<0.05). A decreased number of cystic follicles and an increased number of primary, antral and graaffian
follicles as well as corpus luteum werealso seen in the PCOS group + 400 mg/kg of Palm pollen extract compared
to the PCOS group. Palm pollen extract can improve tissue symptoms and adjust the levels of sex hormones in
polycystic ovary syndrome.

Keywords: Palm Pollen, Polycystic Ovary Syndrome, Rat

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