End stage renal disease (ESRD) is a condition with an irreversible loss of renal function. The two major treatment options are transplantation and dialysis; hemodialysis (HD) or peritoneal dialysis (PD). In this study, we aimed to evaluate the effect of HD vs. PD on quality of life (QOL) in these patients. This cross sectional study recruited 140 PD and HD patients in the range of 15-65 years old from two main dialysis centers of Shiraz University of Medical Sciences, Iran. After obtaining some demographic data, patients were asked to complete the the Kidney Disease Quality of Life- Short Form (KDQOL-SF) questionnaire. Statistical analyses were performed using the SPSS 20.0 for Windows. Of the 140 participants in this study, 68 (48.57%) were on HD and 72 (51.43%) were on PD. PD patients had better score in sleep, kidney disease effect, social functioning, pain, etc. were differed significantly from HD patients. Overall QOL score had better for PD patients (p = 0.008). This study provides evidence that QOL in PD is better than HD patients. These results could become in use particularly in the planning of health care policies and patient management.
Key words: ESRD, Hemodialysis, Peritoneal dialysis, Quality of life