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Sero- Epidemiological trends of Dengue Fever in Jammu Province of J&K State

Authors: Sudhan S. Shashi, Sharma Monika, Gupta Rajiv Kumar and Sambyal S. Sorabh

Int J Med Res Health Sci.1-6 | pdf PDF Full Text

ABSTRACT
Dengue, an arthropod-borne arboviral disease is becoming a major public health concern, both in the tropical and
subtropical regions of the world. In view of exponential increase in dengue positive cases reported in year 2103 the
authors decided to follow the emerging trends of the disease over a period of five years wef 2011 t0 2015 . The
laboratory records of clinically suspected Dengue patients from 2011 to 2015 were analyzed retrospectively for the
results of IgM anti dengue antibodies tested by Dengue IgM capture enzyme linked immune sorbent assay (MAC
ELISA) along with demographic features, and seasonal variations. A total of five thousand nine hundred fifty
(5950) samples from patients suspected of dengue infection were received and screened for the presence of dengue
specific IgM antibodies. 1891/5950 (31.78%) of the samples were found to be positive. The association between
serum samples and different age groups was found to be highly significant (p=0.0000). Dengue infection has
become an endemic disease in this region occurring annually. In absence of specific treatment and vaccine for
dengue fever (DF); early diagnosis is important in management of infection. This also demands continuous
seroepidemiological surveillance for the timely formulation and implementation of effective dengue control
programme. Moreover, serological cross reactivity with other Flaviviruses was unexpected in Jammu, for their
absence .
Key words: Seroepidemiology, Dengue fever, IgM antibody capture enzyme linked immune sorbent assay (MAC
ELISA), India, Vector.

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