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Role of prebiotic and probiotic in the management of chronic kidney disease patients

Authors: Mathew George, Lincy Joseph and Deepa George

Int J Med Res Health Sci.2016, 5, 2:50-53 | pdf PDF Full Text

Chronic Kidney disease is more common in Indian population today. Hence the need of medications for chronic
kidney disease also increased now a days. This study is designed to investigate the role of Prebiotics and probiotics
in the management of chronic kidney disease patient. Oral administration of a probiotic formulation of selected
microbial strains may extend renoprotection via intraintestinal extraction of toxic waste solutes in patients with
chronic kidney disease (CKD) . The idea behind the research is to prevent the development of key damaging uremic
toxins by targeting the process of bacterial protein fermentation in the gut. People with kidney disease have been
shown to have a disturbed gut flora, which promotes the increased production of those harmful toxins. By
supplementing patients with a specific combination of bacteria (probiotics) and beneficial fibre to support the
growth of the good bacteria (prebiotics), it improve the health of the gut, suppressing the growth of bad bacteria
and therefore decreasing the production of the toxins. In turn this should assist in delaying further kidney disease
progression and improve heart health.
Key words: Chronic kidney disease, probiotics, prebiotics, Uremic toxins

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