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Rare association of Fahr’s disease with multiple myeloma: A case report


Int J Med Res Health Sci. |

Authors: Tripathy KP, Behera PK, Dalai RK, Misra GC
Int J Med Res Health Sci.2014;3(3):774-778 |   DOI:10.5958/2319-5886.2014.00438.X


Fahrs disease or Fahrs syndrome is a rare neurological disorder   characterized by abnormal calcified deposits in the basal ganglia and cerebral cortex. 47 years male who presented to us with progressive ataxia and Parkinsonian symptoms was found to have extensive bilateral calcifications including bilateral basal ganglia in CT scan of the brain. The secondary causes of intracranial calcifications were ruled out to make a clinical diagnosis of Fahrs disease. While investigating for chronic low back pain with anemia and renal failure, high ESR and serum protein electrophoresis showing M band was detected. On further investigation, the bone marrow study confirmed the diagnosis of multiple myeloma. There are only few case reports of association of Fahr’s disease and multiple myeloma in literature. The case is being reported here in view of rarity.

Key words: Fahr’s disease, Bilateral intracranial calcifications, Multiple myeloma, M-Band, Plasma cells.

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