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Radiological (MRI) and Biochemical effects of Low Level LASER therapy in chronic Osteo arthritis in Al-Kharj, Saudi Arabia: A Randomized Control Trial

Authors: Gopal Nambi S., Walid Kamal Mohammed Abdel Basset, JuliSaji George and Elbagir Hamza Mohamed Ali

Int J Med Res Health Sci.318-325 | pdf PDF Full Text

Osteoarthritis is one of the degenerative diseases and Low level laser therapy (LLLT) has been prescribed as nonoperative treatment in physiotherapy. But the available evidences of finding the radiological and biochemical
effectiveness of LLLT are very few. So, the purpose of this study is to find the radiological and biochemical effect of
Low level laser therapy (LLLT) in the treatment of Osteoarthritis. 34 subjects who fulfilled the inclusion and
exclusion criteria were divided into two groups (Active Laser group – ALG & Placebo Laser group – PLG) with
randomized sampling method. ALG was treated with active laser head, whereas PLG treated same like ALG but
without emission of energy. Both groups were applied with kinesio tape for 4 weeks. The frequency of the treatment
was three times per week for 4 weeks in both groups. Subjects were assessed at baseline, 4
th and 8th week. Contact
area (mm
2) – medial & lateral and cartilage thickness (percentage) – medial & lateral was measured by Magnetic
resonance image (MRI) and CTX-II (µmg/mmol) was measured by urine analysis. A statistically significant (p

0.05) difference between both groups were noted at the period of 8 week for contact area (lateral) and CTX-II and
insignificant (p
0.05) difference in contact area (medial) and cartilage thickness (medial & lateral) were noted. In
conclusion, the low level laser therapy is helpful in modifying the biochemical components and leads to make
changes in the cartilage which subsequently improve the quality of life of OA patients

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