Authors: Pankaj K. Gadhia, Salil N. Vaniawala
The prevalence of Prader-Willi Syndrome (PWS) was studied using both classic cytogenetic and FISH techniques in referred cases of microdeletion 15q11-13 to our laboratory from Western India. A total of 53 cases were registered, of which 08(15%) were found positive for Prader-Willi Syndrome i.e. 15q11-13 microdeletion syndrome. FISH technique found to be suitable and sensitive to confirm clinically diagnosed PWS.
Keywords: Prader-Willi syndrome, Western India, FISH, 15q11-13