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Late onset hemorrhagic disease of newborn due to CMV hepatitis presenting as scalp hematoma

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Int J Med Res Health Sci. |

Authors: Amit Yadav, Shrikhande DY, Rajib Chatterjee, Amit Narkhede, Amol pokharkar, Santosh Yadav
Int J Med Res Health Sci. 2013;2(4):1021-1023 |   | DOI:10.5958/j.2319-5886.2.4.170

ABSTRACT 

Vitamin K deficiency bleeding (VKDB) according to recent studies is the preferred term for hemorrhagic disease of the newborn (HDN). This is due to deficiency of clotting factors as a result of vitamin K deficiency. VKDB was first described over a hundred years ago but its relationship to vitamin K was not released until 40 years later. Vitamin K is required for the production of clotting factors II, VII, IX and X. It is involved in the normal clotting of blood, is present in some plants and is also synthesized by some E. coli in the gut. Due to low levels of vitamin K all newborn infants are at risk of developing hemorrhagic disease of the newborn. The body has very limited ability to store the vitamin. We present an unusual case of Neonatal Hepatitis due to CMV as a rare cause of late onset vitamin k-deficiency bleeding.

Keywords: Cholestatic liver disease, Vitamin K, Vitamin K deficiency bleeding.

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