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Investigating the influence of local antiseptics on the level of urinary tract infection (UTI) among patients undergoing transrectalbiopsy of prostate

Authors: Sodabeh Nikfarjam and Seyed Morteza Bagheri

Int J Med Res Health Sci.73-76 | pdf PDF Full Text

Transrectal ultrasound guided biopsy of the prostate is the most common modality used to diagnose prostate cancer.
The main complication of this modality is prostatitis. The purpose of this study is to determine the effect of simple
use of suppository povidone-iodine on infectious complications after transrectal ultrasonography-guided biopsy of
the prostate. In a randomized clinical trial, 300 patients are included and received antibiotic prophylaxis. Among
them, 150 patients received povidone-iodine suppository five minutes prior to biopsy (group 1) and 150 patients did
not (group 2). Infectious complications were compared in two groups. Urinary tracts infection were not detected in
the rectal preparation group (Group 1) and developed in 13 cases (8.8%) in the non-rectal preparation group
(Group 2) (odds ratio=0.912; P<0.001). Prostatitis was not detected in the rectal preparation group (Group 1) and
developed in 13 cases (8.8%) in the non-rectal preparation group (Group 2) (odds ratio=0.912; P<0.001).
Povidone-iodine into the rectum and decreased the bacterial colony count. Simple use of povidone-iodine
suppository before prostate biopsy minimizes the risk of infectious complications

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