The effects of cigarette smoking are fatal. Present study was done to compare cell counts of blood in males smoking
different number of cigarettes per day and non smokers of Hyderabad city. 150 consenting subjects of which 30
controls (non-smokers) and 120 cases (smokers) were studied. Smokers were divided into four groups based on
number of cigarettes smoked per day. Blood samples processed using Hematology analyser (ABX Micros60®,
HORIBA, Kyoto, Japan). The smokers had significantly different red blood cell counts (p<0.0001), white blood cells
counts (p<0.0001) including neutrophils, lymphocytes, monocytes and eosinophils. This effect was significant
irrespective of the number of cigarettes. There was no significant change in the percentage of basophils and platelet
counts. Conclusion: Our findings showed that cigarette smoking has a significant effect on hematological cell
counts and these counts changed significantly with increasing number of cigarettes smoked per day.
Keywords: Smoking, Total Leucocyte count, Differential Leucocyte count, Red Blood cell count, Platelet count.