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Comparative study of gonadotropin levels and clinical presentation in surgical and natural menopause

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Int J Med Res Health Sci. |

Authors: Naik Raviraj R, Chandel Rittu S, Abichandani Leela G
Int J Med Res Health Sci.2014;3(1):149-154 |   | DOI:10.5958/j.2319-5886.3.1.029

ABSTRACT

Introduction: Menopause means complete stoppage of menses for last one year due to failure of follicular activities of the ovaries. This  can  be  determined  by  the various hormones  secreted  by ovary  such  as LH  and  FSH. As  these hormones  are  responsible  for  normal  maintenance  of  basic  ovarian  function  in  reproductive  life; there  occurs  considerable  alteration  in their  levels in  menopause. Aims and  Objectives :-    1] To  study  and  compare ovarian  function  by  determining  levels  of  LH  and  FSH  in Surgical and Natural  menopause.  2] To  study  and  compare  ovarian  function  in  Surgical and  Natural  menopause. Brief Methodology: –  Case study: –  50  women  with  surgical  menopause  between  45 – 50 years  of  age. Control study: – 50 women with natural menopause between 45 – 50 years of age. Material & Methodolgy :- Fasting  serum samples of  all women  with  surgical  and  natural menopause  were  analysed  for  LH  and  FSH  on Immulite 1000  chemiluminiscence based  analyser  in  special  investigation lab. Summary of the Results:-  Mean  levels of  LH  and FSH were  higher  in  surgical  menopausal  women  as  compared  to  natural  menopausal  women. Women in surgical menopause suffered from more vasomotor symptoms and cognitive decline as compared to women in natural menopause group

Keywords: Surgical menopause, Natural menopause, LH, FSH, Chemiluminiscence

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