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Comparative evaluation of Azelastine and fluorometholone in the treatment of spring catarrh (vernal catarrh)


Int J Med Res Health Sci. |

Author: Ather Mohammed, Nasreen
Int J Med Res Health Sci.2014;3(4):866-869 | | DOI: 10.5958/2319-5886.2014.00016.2


Aim and Objective: To study and compare the efficacy of FML &Azelastin eye drops in relieving symptoms & regressing signs of VKC. Methodology: This Prospective Interventional study conducted at Sarojini Devi eye hospital, Hyderabad which is a regional institute of Ophthalmology during the period July 2004 to July 2005. The 100 patients of spring catarrh reported to SD eye hospital during the period were randomly divided into 2 groups of 50 each. Group I were given Fluorometholone 0.25% eye drops four times daily for a period of 4 weeks. Group II were given AzelastineHCl 0.05% eye drops four times daily for a period of 4 weeks. Results:Documented by taking symptomatic relief of patient, Clinical improvement of signs, reduction in Eosinophils and Mast cells on histopathological examination. Conclusion: This study shows that Fluorometholone is superior to Azelastine in relieving Symptoms and regression of signs in the cases of Vernal catarrh.

Keywords: Vernalkeratoconjunctivitis (VKC), FML(Fluorometholone), Azelastine,Eosinophils, Mast cells

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