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Clinicopathological study of prostate lesions-A one year study

Authors: Wasim Khatib, Sunil Jagtap, Rakesh Demde, Dhirajkumar Buddhiram Shukla and Tasneem Bisht

Int J Med Res Health Sci.183-186 | pdf PDF Full Text

In Prostate, benign as well as malignant conditions are seen frequently with advancing age. By this study we aim to analyse the various lesions in patients presenting to our rural hospital. Total of 88 specimens were studied from October 2014 to September 2015. Lesions were graded into inflammatory, infectious, benign and malignant lesions. PSA levels were correlated wherever available. Gleason grading was used to grade all adenocarcinoma. 72 cases of TURP specimen, 06 cases & 10 cases of prostatectomies & needle biopsies respectively were found. Most common age was 6th-8thdecade. Most common complaints were urgency and difficulty in voiding. PSA levels were normal in 23 cases, others showed variable increase. BPH constituted majority of the cases, 45(51%) with 28(31.81%) of PIN, 10 (11.36%) of adenocarcinoma, 2 of granulomatous & ANH & 1 of Xanthogranulomatous prostatitis. BPH was most commonly encountered lesion followed by PIN and adenocarcinoma. PSA levels are not specific for prostate cancer as they can be alleviated in various other conditions. The degree of elevation of PSA along with clinical correlation can aid in diagnosis.
 

Keywords: Prostatitis, adenocarcinoma, Prostatic intraepithelial neoplasia

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